[Download pdf] Gene Essentiality: Methods and Protocols (Methods in Molecular Biology)






 | #6394402 in Books |  Ingramcontent |  2015-01-31 | Original language:English | PDF # 1 |  10.00 x.63 x7.00l,1.48 | File Name: 1493923978 | 248 pages

 | Gene Essentiality Methods and Protocols Methods in Molecular Biology


||From the Back Cover||This volume opens by covering two main types of approaches widely used to determine essential genes: single-gene knockouts and transposon mutagenesis, in both prokaryotes and Candida albicans. Given the significant advancement in the

This volume opens by covering two main types of approaches widely used to determine essential genes: single-gene knockouts and transposon mutagenesis, in both prokaryotes and Candida albicans. Given the significant advancement in the computational predictions of microbial essential genes, the second half of the book examines four main types of approaches: comparative genomics, supervised machine learning, constraint-based methods, and corrections of transposon...


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